Pub. Date : 2013 Aug
PMID : 23743668
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Genetic polymorphisms in ABCB1 influence the pharmacodynamics of tacrolimus. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | In addition, the ABCB1 genotype of 36 tacrolimus-treated renal transplant patients was related to ABCB1 activity and tacrolimus efficacy. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | In addition, the ABCB1 genotype of 36 tacrolimus-treated renal transplant patients was related to ABCB1 activity and tacrolimus efficacy. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | In addition, the ABCB1 genotype of 36 tacrolimus-treated renal transplant patients was related to ABCB1 activity and tacrolimus efficacy. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | This effect on tacrolimus pharmacodynamics was associated with ABCB1 3435C>T SNP in renal transplant patients: verapamil reduced the percentage of IL-2-producing CD4 and CD8 T cells by 14% and 22% in patients with the CC genotype (P < 0.05) but not in patients with the TT genotype. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 6 | CONCLUSION: The ABCB1 3435C>T SNP influences ABCB1 activity of T cells and the pharmacodynamic effect of tacrolimus in kidney transplant patients. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 7 | CONCLUSION: The ABCB1 3435C>T SNP influences ABCB1 activity of T cells and the pharmacodynamic effect of tacrolimus in kidney transplant patients. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |