Title : Impact of severe hypothyroidism on cyclophosphamide disposition and routes of metabolism and transport in a patient with treatment-resistant lupus nephritis.

Pub. Date : 2013 Jul-Aug

PMID : 23737517






1 Functional Relationships(s)
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1 The pharmacokinetics of the probe drug cocktail (flurbiprofen/fexofenadine) were altered, with formation clearance of flurbiprofen (CYP2C9 function) lower in our patient versus the average value in our study cohort, suggesting a reduction in activity. Flurbiprofen cytochrome P450 family 2 subfamily C member 9 Homo sapiens