Title : Apoptosis induced by paclitaxel via Bcl-2, Bax and caspases 3 and 9 activation in NB4 human leukaemia cells is not modulated by ERK inhibition.

Pub. Date : 2013 Nov

PMID : 23735541






1 Functional Relationships(s)
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1 When these cells were preincubated for 90min with 20muM PD98059, 2"-amino-3"-methoxyflavone, an inhibitor of ERK phosphorylation, a slight reduction of cell viability was observed in comparison to that produced by Ptx alone. Paclitaxel mitogen-activated protein kinase 1 Homo sapiens