Title : Protective effects of selective mineralocorticoid receptor antagonist against aortic aneurysm progression in a novel murine model.

Pub. Date : 2013 Nov

PMID : 23731681






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Real-time polymerase chain reaction of both aortic wall and perivascular adipose tissue demonstrated the expression of tumor necrosis factor-alpha, interleukin-6, and matrix metalloproteinase-2 was significantly decreased in eplerenone group, and that of monocyte chemoattractant protein-1 in the aortic wall was also significantly decreased. Eplerenone interleukin 6 Mus musculus
2 The production of tumor necrosis factor-alpha and interleukin-6 in macrophage culture, which was stimulated by high mobility group box-1 and CpG oligodeoxynucleotides, was also significantly decreased in the eplerenone group. Eplerenone interleukin 6 Mus musculus