Title : In vitro to in vivo evidence of the inhibitor characteristics of Schisandra lignans toward P-glycoprotein.

Pub. Date : 2013 Aug 15

PMID : 23731657






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Verapamil, a known P-gp inhibitor, was used as a positive control drug. Verapamil ATP binding cassette subfamily B member 1 Homo sapiens
2 Results shown that, 10 muM verapamil and SLE (0.5, 2.0, and 10.0 mug/ml) were observed to significantly enhance the uptake and inhibit the efflux ratio of P-gp substrates in Caco-2 and L-MDR1 cells. Verapamil ATP binding cassette subfamily B member 1 Homo sapiens