Pub. Date : 2013 Oct
PMID : 23727220
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Whole-cell patch-clamp recordings showed a marked potentiation of the inward current responses both to ATP and the prototypic P2X7 receptor agonist dibenzoyl-ATP (Bz-ATP) at low Ca(2+) and zero Mg(2+) concentrations in the bath medium. | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | purinergic receptor P2X, ligand-gated ion channel, 7 | Mus musculus |
| 2 | The general P2X/P2Y receptor antagonist PPADS and the P2X7 selective antagonists Brilliant Blue G and A-438079 strongly depressed the effect of Bz-ATP. | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | purinergic receptor P2X, ligand-gated ion channel, 7 | Mus musculus |
| 3 | Correspondingly, Bz-ATP led to an increase in active caspase 3 immunoreactivity, indicating a P2X7-controlled apoptosis. | 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | purinergic receptor P2X, ligand-gated ion channel, 7 | Mus musculus |