Title : Free cholesterol determines reassembled high-density lipoprotein phospholipid phase structure and stability.

Pub. Date : 2013 Jun 25

PMID : 23721456






2 Functional Relationships(s)
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Protein Name
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1 DSC studies reveal multiple phases or domains that can be classified as virtual DMPC, which contains a small amount of DMPC that slightly reduces the melting temperature (Tm), a boundary phase that is adjacent to the apo A-I or apo A-II that circumscribes the discoidal rHDL, and a mixed FC/DMPC phase that has a Tm that increases with FC mole percent. Dimyristoylphosphatidylcholine apolipoprotein A1 Homo sapiens
2 For rHDL (apo A-II) compared to rHDL (apo A-I), this occurs in spite of the reduced number of helical regions that mediate binding to the DMPC surface. Dimyristoylphosphatidylcholine apolipoprotein A1 Homo sapiens