Pub. Date : 2013 Aug 1
PMID : 23720056
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mechanistic studies showed that the cisplatin-induced cytoplasmic TR3 translocation required for apoptosis induction was regulated by JNK activation and inhibition of Akt. | Cisplatin | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | Finally, cisplatin resistance was partially overcome by ectopic TR3 overexpression and by treatment with the JNK activator anisomycin and Akt pathway inhibitor, wortmannin. | Cisplatin | mitogen-activated protein kinase 8 | Homo sapiens |