Pub. Date : 2013 May 29
PMID : 23719800
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Role of the major glutamate transporter GLT1 in nucleus accumbens core versus shell in cue-induced cocaine-seeking behavior. | Cocaine | solute carrier family 1 member 2 | Rattus norvegicus |
2 | Decreased expression of glutamate type I transporter (GLT1), which is responsible for >90% of glutamate clearance, occurs in the core of rats withdrawn from cocaine self-administration, while treatment with ceftriaxone, a beta-lactam antibiotic previously shown to increase GLT1 expression and function in rodents, upregulates GLT1 and attenuates cue-induced cocaine reinstatement. | Cocaine | solute carrier family 1 member 2 | Rattus norvegicus |
3 | Decreased expression of glutamate type I transporter (GLT1), which is responsible for >90% of glutamate clearance, occurs in the core of rats withdrawn from cocaine self-administration, while treatment with ceftriaxone, a beta-lactam antibiotic previously shown to increase GLT1 expression and function in rodents, upregulates GLT1 and attenuates cue-induced cocaine reinstatement. | Cocaine | solute carrier family 1 member 2 | Rattus norvegicus |