Title : Epidermal adrenergic signaling contributes to inflammation and pain sensitization in a rat model of complex regional pain syndrome.

Pub. Date : 2013 Aug

PMID : 23718987






1 Functional Relationships(s)
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1 Based on these in vitro results, we returned to animal testing and observed that the selective beta2-AR antagonist butoxamine reduced nociceptive sensitization in the CRPS model, and that local injection of the selective beta2-AR agonist terbutaline resulted in mechanical allodynia and the production of IL-6 in the cells of the skin. Terbutaline adrenoceptor beta 2 Rattus norvegicus