Pub. Date : 2013 Aug
PMID : 23712703
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | However, the receptor for advanced glycation end products (RAGE) blocker RAGE-Ab (5 mug/ml) or 10 muM c-Jun N-terminal kinases (JNK) inhibitor SP600125 could inhibit HMGB1-induced the release of inflammation cytokines including TNF-alpha, IL-8, IL-10, and MCP-1 in a dose-dependent manner. | pyrazolanthrone | advanced glycosylation end-product specific receptor | Homo sapiens |
2 | Furthermore, HMGB1-induced RAGE protein expression, JNK and NF-kappaB activation were attenuated by the pretreatment with RAGE-Ab or JNK inhibitor SP600125 in Western blot analysis. | pyrazolanthrone | advanced glycosylation end-product specific receptor | Homo sapiens |