Title : Inhibition of x-box binding protein 1 reduces tunicamycin-induced apoptosis in aged murine macrophages.

Pub. Date : 2013 Oct

PMID : 23711292






1 Functional Relationships(s)
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1 We found that aged macrophages exhibited more apoptosis than young macrophages, which was accompanied by reduced activation of phosphorylated inositol-requiring enzyme-1 (p-IRE1alpha), one of the three key ER stress signal transducers. Inositol endoplasmic reticulum (ER) to nucleus signalling 1 Mus musculus