Title : Approaches for monitoring PKG1α oxidative activation.

Pub. Date : 2013

PMID : 23709032






4 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 cGMP-dependent protein kinase, also known as protein kinase G (PKG), is activated independently of cGMP by a novel thiol-reactive mechanism involving the formation of an intermolecular disulfide. Disulfides protein kinase cGMP-dependent 1 Homo sapiens
2 cGMP-dependent protein kinase, also known as protein kinase G (PKG), is activated independently of cGMP by a novel thiol-reactive mechanism involving the formation of an intermolecular disulfide. Disulfides protein kinase cGMP-dependent 1 Homo sapiens
3 Here, we describe the proteomic approach that lead to PKG being identified as a kinase susceptible to oxidant-dependent disulfide dimer formation, these methods being applicable for the identification of other disulfide bound protein complexes. Disulfides protein kinase cGMP-dependent 1 Homo sapiens
4 Here, we describe the proteomic approach that lead to PKG being identified as a kinase susceptible to oxidant-dependent disulfide dimer formation, these methods being applicable for the identification of other disulfide bound protein complexes. Disulfides protein kinase cGMP-dependent 1 Homo sapiens