Title : Cleavage of bleomycin hydrolase by caspase-3 during apoptosis.

Pub. Date : 2013 Aug

PMID : 23708668






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Bleomycin hydrolase (BLH) affects bleomycin chemotherapy through inactivation of bleomycin with deamination. Bleomycin bleomycin hydrolase Homo sapiens
2 Bleomycin hydrolase (BLH) affects bleomycin chemotherapy through inactivation of bleomycin with deamination. Bleomycin bleomycin hydrolase Homo sapiens
3 Bleomycin hydrolase (BLH) affects bleomycin chemotherapy through inactivation of bleomycin with deamination. Bleomycin bleomycin hydrolase Homo sapiens
4 Bleomycin hydrolase (BLH) affects bleomycin chemotherapy through inactivation of bleomycin with deamination. Bleomycin bleomycin hydrolase Homo sapiens
5 In the present study, we showed that the levels of BLH were significantly reduced during apoptosis induced by the antitumor agents bleomycin, etoposide and hydroxycamptothecin, and inhibited by the caspase inhibitors Q-VD-oph and Z-DEVD-FMK. Bleomycin bleomycin hydrolase Homo sapiens