Title : FK506 induces endothelial dysfunction through attenuation of Akt and ERK1/2 independently of calcineurin inhibition and the caspase pathway.

Pub. Date : 2013 Sep

PMID : 23707520






3 Functional Relationships(s)
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1 FK506 induces endothelial dysfunction through attenuation of Akt and ERK1/2 independently of calcineurin inhibition and the caspase pathway. Tacrolimus AKT serine/threonine kinase 1 Homo sapiens
2 FK506 induced attenuation of Akt and extracellular-regulated kinase 1/2 (ERK1/2). Tacrolimus AKT serine/threonine kinase 1 Homo sapiens
3 Present results suggest that FK506 induces endothelial dysfunction through attenuation of Akt and ERK1/2 independently of calcineurin inhibition and the caspase pathway. Tacrolimus AKT serine/threonine kinase 1 Homo sapiens