Title : Effects of CYP3A5 and CYP2D6 genetic polymorphism on the pharmacokinetics of diltiazem and its metabolites in Chinese subjects.

Pub. Date : 2013 Apr

PMID : 23700791






2 Functional Relationships(s)
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1 Effects of CYP3A5 and CYP2D6 genetic polymorphism on the pharmacokinetics of diltiazem and its metabolites in Chinese subjects. Diltiazem cytochrome P450 family 3 subfamily A member 5 Homo sapiens
2 PURPOSE: To assess the possibility of using CYP2D6 10 +/- CYP3A5*3 as biomarkers to predict the pharmacokinetics of diltiazem and its two metabolites among healthy Chinese subjects. Diltiazem cytochrome P450 family 3 subfamily A member 5 Homo sapiens