Title : Structure and kinetic analysis of H2S production by human mercaptopyruvate sulfurtransferase.

Pub. Date : 2013 Jul 5

PMID : 23698001






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The crystal structure analysis allows us to propose a detailed mechanism for MST in which an Asp-His-Ser catalytic triad is positioned to activate the nucleophilic cysteine residue and participate in general acid-base chemistry, whereas our kinetic analysis indicates that thioredoxin is likely to be the major physiological persulfide acceptor for MST. 2-(3,5-dihydroxyphenyl)-6-hydroxybenzothiazole thioredoxin Homo sapiens