Pub. Date : 2013 May 20
PMID : 23688423
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TNF-alpha and LPA promote synergistic expression of COX-2 in human colonic myofibroblasts: role of LPA-mediated transactivation of upregulated EGFR. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |
| 2 | Here, we investigate whether EGFR signaling plays a role in the synergistic COX-2 expression induced by LPA and TNF-alpha. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |
| 3 | However, chronic exposure to TNF-alpha led to upregulation of EGFR in association with sustained LPA-mediated EGFR phosphorylation at Y1068. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |
| 4 | However, chronic exposure to TNF-alpha led to upregulation of EGFR in association with sustained LPA-mediated EGFR phosphorylation at Y1068. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |