Title : Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-κB survival pathway in A375-S2 cells.

Pub. Date : 2013 Jul 9

PMID : 23684722






2 Functional Relationships(s)
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1 Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-kappaB survival pathway in A375-S2 cells. Reactive Oxygen Species tumor protein p53 Homo sapiens
2 CONCLUSIONS: Physalin A induced apoptotic cell death via p53-Noxa-mediated ROS generation, and autophagy played a protective role against apoptosis through up-regulating the p38-NF-kappaB survival pathway in A375-S2 cells. Reactive Oxygen Species tumor protein p53 Homo sapiens