Title : Activation of the nuclear receptor FXR enhances hepatocyte chemoprotection and liver tumor chemoresistance against genotoxic compounds.

Pub. Date : 2013 Oct

PMID : 23680185






1 Functional Relationships(s)
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1 In human hepatoma Alexander cells, with negligible endogenous expression of FXR, GW4064 also protected against cisplatin-induced toxicity, but only if they were previously transfected with FXR/RXR. GW 4064 retinoid X receptor alpha Homo sapiens