Pub. Date : 2013
PMID : 23675509
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treating the IGF-1R deficient myoblasts with H2O2 resulted in significantly higher phosphorylation of Akt as compared to cells having normal expression of IGF-1R. | Hydrogen Peroxide | insulin-like growth factor I receptor | Mus musculus |
| 2 | Treating the IGF-1R deficient myoblasts with H2O2 resulted in significantly higher phosphorylation of Akt as compared to cells having normal expression of IGF-1R. | Hydrogen Peroxide | insulin-like growth factor I receptor | Mus musculus |
| 3 | However, in NIH-3T3 fibroblasts and MC3T3-E1 osteoblasts, the loss of IGF-1R by siRNA directed knockdown was associated with reduced levels of phosphorylated Akt on treatment with H2O2 or UV as compared to control cells and these cells showed more apoptosis. | Hydrogen Peroxide | insulin-like growth factor I receptor | Mus musculus |