Title : [Design, synthesis and cholinesterase inhibitory activity of quinoline-polyamine conjugates].

Pub. Date : 2013 Feb

PMID : 23672025






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Compound 8n exhibited the strongest inhibition on acetylcholinesterase (AChE) with an IC50 value of 8.78 micromol x L(-1), and compound 8i showed the most potent inhibition on butyrylcholinesterase (BChE) with IC50 value of 1.60 micromol x L(-1) which was slightly better than rivastigmine. Rivastigmine acetylcholinesterase (Cartwright blood group) Homo sapiens