Title : Blocking retinoic acid receptor-α enhances the efficacy of a dendritic cell vaccine against tumours by suppressing the induction of regulatory T cells.

Pub. Date : 2013 Jul

PMID : 23657628






1 Functional Relationships(s)
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1 We found that RA significantly enhanced TGF-beta-induced expression of Foxp3 on naive and committed T cells in vitro and that this was blocked by an antagonist of RARalpha (RARi). Tretinoin forkhead box P3 Mus musculus