Title : PD-L1/B7-H1 regulates the survival but not the function of CD8+ T cells in herpes simplex virus type 1 latently infected trigeminal ganglia.

Pub. Date : 2013 Jun 15

PMID : 23656736






2 Functional Relationships(s)
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1 In C57BL/6 mice, the TG-resident CD8(+) T cells are HSV specific and maintain a 1:1 ratio of cells recognizing an immunodominant epitope on viral glycoprotein B (gB498-505-Tet(+)) and cells reactive to subdominant epitopes (gB-Tet(-)). tetramethylenedisulfotetramine CD8a molecule Homo sapiens
2 The gB-Tet(-) CD8(+) T cells maintain their frequency in TG by balancing a higher rate of proliferation with a correspondingly higher rate of apoptosis. tetramethylenedisulfotetramine CD8a molecule Homo sapiens