Title : OSU-03012, a non-Cox inhibiting celecoxib derivative, induces apoptosis of human esophageal carcinoma cells through a p53/Bax/cytochrome c/caspase-9-dependent pathway.

Pub. Date : 2013 Aug

PMID : 23652278






1 Functional Relationships(s)
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1 An inhibitor of p53, pifithrin-alpha, attenuated the anticancer effects of OSU-03012 and downregulated the expression of Bax and cleaved caspase-9. pifithrin tumor protein p53 Homo sapiens