Title : Cholesterol affects gene expression of the Jun family in colon carcinoma cells using different signaling pathways.

Pub. Date : 2013 Jul 15

PMID : 23643895






2 Functional Relationships(s)
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1 Specific inhibition of p-Akt by wortmannin did not affect cholesterol"s stimulation of the expression of c-Jun and Jun-B, however the vanadate effect of increasing p-ERK1/2, inhibited c-Jun expression, specifically, and the MBCD effect of increasing p-ERK and inhibiting p-Akt reduced c-Jun expression. Vanadates jun proto-oncogene Mus musculus
2 Specific inhibition of p-Akt by wortmannin did not affect cholesterol"s stimulation of the expression of c-Jun and Jun-B, however the vanadate effect of increasing p-ERK1/2, inhibited c-Jun expression, specifically, and the MBCD effect of increasing p-ERK and inhibiting p-Akt reduced c-Jun expression. Vanadates jun proto-oncogene Mus musculus