Pub. Date : 1990 May 22
PMID : 2364062
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Binding of benzo[a]pyrene to DNA by cytochrome P-450 catalyzed one-electron oxidation in rat liver microsomes and nuclei. | Benzo(a)pyrene | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 2 | The specific cytochrome P-450 inhibitor 2-[(4,6-dichloro-o-biphenyl)oxy]ethylamine hydrobromide (DPEA) reduced or eliminated BP metabolism, binding of BP to DNA, and formation of BP-N7Gua by cytochrome P-450 in both microsomes and nuclei. | Benzo(a)pyrene | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 3 | The specific cytochrome P-450 inhibitor 2-[(4,6-dichloro-o-biphenyl)oxy]ethylamine hydrobromide (DPEA) reduced or eliminated BP metabolism, binding of BP to DNA, and formation of BP-N7Gua by cytochrome P-450 in both microsomes and nuclei. | Benzo(a)pyrene | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 4 | The specific cytochrome P-450 inhibitor 2-[(4,6-dichloro-o-biphenyl)oxy]ethylamine hydrobromide (DPEA) reduced or eliminated BP metabolism, binding of BP to DNA, and formation of BP-N7Gua by cytochrome P-450 in both microsomes and nuclei. | Benzo(a)pyrene | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |