Title : Mammalian mucosal α-glucosidases coordinate with α-amylase in the initial starch hydrolysis stage to have a role in starch digestion beyond glucogenesis.

Pub. Date : 2013

PMID : 23638112






7 Functional Relationships(s)
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1 Mammalian mucosal alpha-glucosidases coordinate with alpha-amylase in the initial starch hydrolysis stage to have a role in starch digestion beyond glucogenesis. Starch alpha-amylase Zea mays
2 Mammalian mucosal alpha-glucosidases coordinate with alpha-amylase in the initial starch hydrolysis stage to have a role in starch digestion beyond glucogenesis. Starch alpha-amylase Zea mays
3 Starch digestion in the human body is typically viewed in a sequential manner beginning with alpha-amylase and followed by alpha-glucosidase to produce glucose. Starch alpha-amylase Zea mays
4 The aim of this study was to investigate how the mucosal alpha-glucosidases act with alpha-amylase to digest granular starch. Starch alpha-amylase Zea mays
5 alpha-Amylase combined with the mucosal alpha-glucosidases in the intestinal extract showed higher glucogenesis as expected, but also higher maltooligosaccharide amounts indicating an overall greater degree of granular starch breakdown. Starch alpha-amylase Zea mays
6 Direct digestion of granular starch by mammalian recombinant mucosal alpha-glucosidases was observed which shows that these enzymes may work either independently or together with alpha-amylase to digest starch. Starch alpha-amylase Zea mays
7 Thus, mucosal alpha-glucosidases can have a synergistic effect with alpha-amylase on granular starch digestion, consistent with a role in overall starch digestion beyond their primary glucogenesis function. Starch alpha-amylase Zea mays