Title : Direct effect of dsRNA mimetics on cancer cells induces endogenous IFN-β production capable of improving dendritic cell function.

Pub. Date : 2013 Jul

PMID : 23636788






1 Functional Relationships(s)
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1 Human A549 lung and DU145 prostate carcinoma cells significantly responded to poly I:C stimulation, producing IFN-beta at levels that were capable of activating STAT1 and enhancing CXCL10, CD40, and CD86 expression on human monocyte-derived DCs. poly I:C CD86 molecule Homo sapiens