Pub. Date : 2013 Jun 1
PMID : 23635904
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A series of heterocyclic quinones based on benzofuran, benzothiophene, indazole and benzisoxazole has been synthesized, and evaluated for their ability to function as substrates for recombinant human NAD(P)H:quinone oxidoreductase (NQO1), a two-electron reductase upregulated in tumor cells. | Quinones | NAD(P)H quinone dehydrogenase 1 | Homo sapiens |
| 2 | Overall, the quinones are excellent substrates for NQO1, approaching the reduction rates observed for menadione. | Quinones | NAD(P)H quinone dehydrogenase 1 | Homo sapiens |