Title : Oatp1a4 and an L-thyroxine-sensitive transporter mediate the mouse blood-brain barrier transport of amyloid-β peptide.

Pub. Date : 2013

PMID : 23635403






1 Functional Relationships(s)
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1 We used in situ brain perfusion to show that rosuvastatin and taurocholate, two established Oatp1a4 substrates, decreased (5-fold) the Clup of [3H]Abeta while L-thyroxine increased it (5.5-fold). Taurocholic Acid amyloid beta (A4) precursor protein Mus musculus