Title : Severe liver cirrhosis markedly reduces AhR-mediated induction of cytochrome P450 in rats by decreasing the transcription of target genes.

Pub. Date : 2013

PMID : 23626760






2 Functional Relationships(s)
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1 We simultaneously assessed mRNA level, protein expression and enzymatic activity of the CYP1A enzymes, as well as mRNA and protein expressions of the aryl hydrocarbon receptor (AhR), which mediates the BP effect. Benzo(a)pyrene aryl hydrocarbon receptor Rattus norvegicus
2 We simultaneously assessed mRNA level, protein expression and enzymatic activity of the CYP1A enzymes, as well as mRNA and protein expressions of the aryl hydrocarbon receptor (AhR), which mediates the BP effect. Benzo(a)pyrene aryl hydrocarbon receptor Rattus norvegicus