Title : ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer.

Pub. Date : 2014 Apr 3

PMID : 23624914






2 Functional Relationships(s)
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Protein Name
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1 Our recent study showed that both ERK and AKT signaling are required to activate eukaryotic translation initiation factor 4E (eIF4E)-initiated cap-dependent translation via convergent regulation of the translational repressor 4E-binding protein 1 (4E-BP1) for maintaining CRC transformation. cap eukaryotic translation initiation factor 4E binding protein 1 Homo sapiens
2 Our recent study showed that both ERK and AKT signaling are required to activate eukaryotic translation initiation factor 4E (eIF4E)-initiated cap-dependent translation via convergent regulation of the translational repressor 4E-binding protein 1 (4E-BP1) for maintaining CRC transformation. cap eukaryotic translation initiation factor 4E binding protein 1 Homo sapiens