Title : Oxime-induced reactivation of acetylcholinesterase inhibited by organophosphinates.

Pub. Date : 1990 Apr

PMID : 2362084






7 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Oxime-induced reactivation of acetylcholinesterase inhibited by organophosphinates. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
2 The comparative potency of oximes for reactivation of inhibited eel acetylcholinesterase (AChE) in vitro is dependent on the organophosphinate inhibitor. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
3 The comparative potency of oximes for reactivation of inhibited eel acetylcholinesterase (AChE) in vitro is dependent on the organophosphinate inhibitor. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
4 This work was done to identify more clearly the nature of phosphinylated AChE with regard to oxime reactivation potency and the potential of phosphinates as pretreatment drugs to protect AChE against organophosphonate poisoning. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
5 Incubation of the inhibited enzyme (I-AChE) at 25 degrees C was with 0.30 microM oxime for PMP, 3.0 microM oxime for sarin and CPMP and 100 microM oxime for the two remaining phosphinates. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
6 Incubation of the inhibited enzyme (I-AChE) at 25 degrees C was with 0.30 microM oxime for PMP, 3.0 microM oxime for sarin and CPMP and 100 microM oxime for the two remaining phosphinates. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
7 Incubation of the inhibited enzyme (I-AChE) at 25 degrees C was with 0.30 microM oxime for PMP, 3.0 microM oxime for sarin and CPMP and 100 microM oxime for the two remaining phosphinates. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens