Title : Oxime-induced reactivation of acetylcholinesterase inhibited by organophosphinates.

Pub. Date : 1990 Apr

PMID : 2362084






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This work was done to identify more clearly the nature of phosphinylated AChE with regard to oxime reactivation potency and the potential of phosphinates as pretreatment drugs to protect AChE against organophosphonate poisoning. phosphinates acetylcholinesterase (Cartwright blood group) Homo sapiens
2 This work was done to identify more clearly the nature of phosphinylated AChE with regard to oxime reactivation potency and the potential of phosphinates as pretreatment drugs to protect AChE against organophosphonate poisoning. phosphinates acetylcholinesterase (Cartwright blood group) Homo sapiens
3 Incubation of the inhibited enzyme (I-AChE) at 25 degrees C was with 0.30 microM oxime for PMP, 3.0 microM oxime for sarin and CPMP and 100 microM oxime for the two remaining phosphinates. phosphinates acetylcholinesterase (Cartwright blood group) Homo sapiens