Title : The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation.

Pub. Date : 2013 Jul 1

PMID : 23613465






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 NLRP3 co-localises with the mitochondria, probably sensing the increase in calcium and the resultant mitochondrial dysfunction, leading to caspase activation and apoptosis. Calcium NLR family pyrin domain containing 3 Homo sapiens