Title : Effects of lovastatin therapy on LDL receptor activity in circulating monocytes and on structure and composition of plasma lipoproteins.

Pub. Date : 1990 May

PMID : 2360916






3 Functional Relationships(s)
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1 Effects of lovastatin therapy on LDL receptor activity in circulating monocytes and on structure and composition of plasma lipoproteins. Lovastatin low density lipoprotein receptor Homo sapiens
2 The effect of lovastatin therapy on LDL-receptor activity in fresh monocytes and on the structure and composition of lipoproteins was determined in 9 patients with familial hypercholesterolemia (FH) and 8 patients with non-familial hypercholesterolemia (NFH). Lovastatin low density lipoprotein receptor Homo sapiens
3 The investigations thus demonstrated that lovastatin therapy is associated with a measurable and significant increase of LDL-receptor activity in circulating monocytes that may contribute to the lipid lowering action of the drug. Lovastatin low density lipoprotein receptor Homo sapiens