Title : Enhancement of thioredoxin production from nasal epithelial cells by the macrolide antibiotic, clarithromycin in vitro.

Pub. Date : 2013 May-Jun

PMID : 23606690






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Nasal epithelial cells (5x10(5) cells/ml) obtained from five patients were stimulated with 50 muM H2O2 in the presence of different concentrations of macrolide antibiotics for 24 h. TRX levels in culture supernatants were examined by enzyme-linked immunosorbent assay. Hydrogen Peroxide thioredoxin Homo sapiens
2 The addition of clarithromycin (CAM) to cell cultures caused an increase in the ability of cells to produce TRX in response to H2O2 stimulation, and the minimum concentration that caused a significant increase was 0.5 mug/ml. Hydrogen Peroxide thioredoxin Homo sapiens