Pub. Date : 2013 Jul
PMID : 23604141
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Antifungal Azoles: Structural Insights into Undesired Tight Binding to Cholesterol-Metabolizing CYP46A1. | Azoles | cytochrome P450 family 46 subfamily A member 1 | Homo sapiens |
| 2 | CYP46A1 is a cholesterol-metabolizing P450 in the brain that tightly binds a number of structurally distinct azoles. | Azoles | cytochrome P450 family 46 subfamily A member 1 | Homo sapiens |
| 3 | These and the solution studies with different marketed azoles, collectively, allowed us to identify the determinants of tight azole binding to CYP46A1 and generate an overall picture of azole binding to this important P450. | Azoles | cytochrome P450 family 46 subfamily A member 1 | Homo sapiens |
| 4 | These and the solution studies with different marketed azoles, collectively, allowed us to identify the determinants of tight azole binding to CYP46A1 and generate an overall picture of azole binding to this important P450. | Azoles | cytochrome P450 family 46 subfamily A member 1 | Homo sapiens |
| 5 | These and the solution studies with different marketed azoles, collectively, allowed us to identify the determinants of tight azole binding to CYP46A1 and generate an overall picture of azole binding to this important P450. | Azoles | cytochrome P450 family 46 subfamily A member 1 | Homo sapiens |