Title : Impact of P-glycoprotein and breast cancer resistance protein on the brain distribution of antiepileptic drugs in knockout mouse models.

Pub. Date : 2013 Jun 15

PMID : 23588114






1 Functional Relationships(s)
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1 In contrast, the Kpbrain values of phenobarbital, clobazam, zonisamide, gabapentin, tiagabine, and levetiracetam in the Mdr1a/1b(-/-)/Bcrp(-/-) mice were significantly higher than the corresponding ones in Mdr1a/1b(-/-) mice. Phenobarbital ATP-binding cassette, sub-family B (MDR/TAP), member 1A Mus musculus