Title : Attenuation of erythrocytic actylcholinesterase by antidepressants: evidence in an in vitro experiment.

Pub. Date : 2015 Oct

PMID : 23572393






4 Functional Relationships(s)
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1 The current study was aimed to scrutinize acetylcholinesterase (AchE) inhibitory profile of two antidepressants, diazepam and phenobarbitone. Diazepam acetylcholinesterase (Cartwright blood group) Homo sapiens
2 The current study was aimed to scrutinize acetylcholinesterase (AchE) inhibitory profile of two antidepressants, diazepam and phenobarbitone. Diazepam acetylcholinesterase (Cartwright blood group) Homo sapiens
3 The results showed marked inhibition of AchE by diazepam and the values of aKm and aVm were 65.5% and 52.63%, respectively. Diazepam acetylcholinesterase (Cartwright blood group) Homo sapiens
4 It is concluded that diazepam and phenobarbitone exhibited prominent AchE attenuation apart from their well-established antidepressant activity, which could be more useful in related diseased conditions. Diazepam acetylcholinesterase (Cartwright blood group) Homo sapiens