Title : Let-7c governs the acquisition of chemo- or radioresistance and epithelial-to-mesenchymal transition phenotypes in docetaxel-resistant lung adenocarcinoma.

Pub. Date : 2013 Jul

PMID : 23562878






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Additionally, siRNA-mediated Bcl-xL knockdown mimicked the same effects of let-7c precursor, and enforced Bcl-xL expression partially rescued the effects of let-7c precursor in DTX-resistant LAD cells. Docetaxel BCL2 like 1 Homo sapiens
2 Furthermore, we found that Bcl-xL was significantly upregulated in DTX-nonresponding LAD tissues, and its expression was inversely correlated with let-7c expression. Docetaxel BCL2 like 1 Homo sapiens