Title : Upregulation of PKCη by PKCε and PDK1 involves two distinct mechanisms and promotes breast cancer cell survival.

Pub. Date : 2013 Aug

PMID : 23562764






1 Functional Relationships(s)
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1 RESULTS: The general PKC inhibitors Go 6983 and bisindolylmaleimide but not cPKC inhibitor Go 6976 led to substantial PKCeta downregulation, which was partly rescued by the introduction of nPKCepsilon. 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide protein kinase C epsilon Homo sapiens