Pub. Date : 2013 Sep 28
PMID : 23562472
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The PI3 kinase inhibitor NVP-BKM120 induces GSK3/FBXW7-dependent Mcl-1 degradation, contributing to induction of apoptosis and enhancement of TRAIL-induced apoptosis. | NVP-BKM120 | TNF superfamily member 10 | Homo sapiens |
| 2 | This study focuses on determining whether and how the novel PI3 kinase inhibitor NVP-BKM120 (BKM120) induces apoptosis and enhances TRAIL-induced apoptosis in human lung cancer cells. | NVP-BKM120 | TNF superfamily member 10 | Homo sapiens |
| 3 | This study focuses on determining whether and how the novel PI3 kinase inhibitor NVP-BKM120 (BKM120) induces apoptosis and enhances TRAIL-induced apoptosis in human lung cancer cells. | NVP-BKM120 | TNF superfamily member 10 | Homo sapiens |
| 4 | We found that BKM120 reduced Mcl-1 levels across the tested cell lines along with induction of apoptosis and enhancement of TRAIL-induced apoptosis. | NVP-BKM120 | TNF superfamily member 10 | Homo sapiens |