Title : Catechol metabolites of the mycotoxin zearalenone are poor substrates but potent inhibitors of catechol-O-methyltransferase.

Pub. Date : 2013 Aug

PMID : 23558779






1 Functional Relationships(s)
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1 The catechol metabolites of ZEN were also shown to inhibit the O-methylation of 2-hydroxy-E2 by hepatic COMT from mouse, rat, steer and piglet, although to a lesser extent than observed with human COMT. catechol catechol-O-methyltransferase Mus musculus