Title : IFN-γ and TNF-α synergistically induce mesenchymal stem cell impairment and tumorigenesis via NFκB signaling.

Pub. Date : 2013 Jul

PMID : 23553791






2 Functional Relationships(s)
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1 Systemic administration of aspirin, which significantly reduces the levels of IFN-gamma and TNF-alpha, results in blockage of MSC deficiency and tumorigenesis by inhibition of NFkappaB/SMAD7 and NFkappaB/c-FOS and c-MYC pathways in OVX mice. Aspirin nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 Systemic administration of aspirin, which significantly reduces the levels of IFN-gamma and TNF-alpha, results in blockage of MSC deficiency and tumorigenesis by inhibition of NFkappaB/SMAD7 and NFkappaB/c-FOS and c-MYC pathways in OVX mice. Aspirin nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus