Pub. Date : 2013 May
PMID : 23551241
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phenobarbital-induced severe cutaneous adverse drug reactions are associated with CYP2C19*2 in Thai children. | Phenobarbital | cytochrome P450 family 2 subfamily C member 19 | Homo sapiens |
| 2 | In subgroup analysis, the patients with CYP2C19*2 variant were at four times increased risk of SCARs from phenobarbital more than the patients with CYP2C19 wild type (OR = 4.5, 95% CI (1.17-17.37) p < 0.03). | Phenobarbital | cytochrome P450 family 2 subfamily C member 19 | Homo sapiens |
| 3 | CONCLUSION: CYP2C19*2 variant may play a role in the genetic predisposition of SCARs from phenobarbital. | Phenobarbital | cytochrome P450 family 2 subfamily C member 19 | Homo sapiens |