Title : Prolonged survival of tumor-bearing rats with repetitive low-dose recombinant tumor necrosis factor.

Pub. Date : 1990 Jul 1

PMID : 2354441






9 Functional Relationships(s)
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1 Following treatment, TB rats that had been treated with rTNF ate significantly more and lost less weight than TB rats that had been treated with saline (P less than 0.00001). Terbium tumor necrosis factor Rattus norvegicus
2 rTNF treatment of TB rats also demonstrated antineoplastic activity, as estimated tumor weight of tumors from rats treated with rTNF were significantly less than controls (P = 0.003). Terbium tumor necrosis factor Rattus norvegicus
3 rTNF treatment of TB rats also demonstrated antineoplastic activity, as estimated tumor weight of tumors from rats treated with rTNF were significantly less than controls (P = 0.003). Terbium tumor necrosis factor Rattus norvegicus
4 The anticachexia and antineoplastic effects of rTNF resulted in prolonged survival of TB rats treated with rTNF compared to control TB rats (P = 0.015). Terbium tumor necrosis factor Rattus norvegicus
5 The anticachexia and antineoplastic effects of rTNF resulted in prolonged survival of TB rats treated with rTNF compared to control TB rats (P = 0.015). Terbium tumor necrosis factor Rattus norvegicus
6 The anticachexia and antineoplastic effects of rTNF resulted in prolonged survival of TB rats treated with rTNF compared to control TB rats (P = 0.015). Terbium tumor necrosis factor Rattus norvegicus
7 Survival of TB rats treated with rTNF was again significantly increased in a dose-dependent manner (P = 0.006). Terbium tumor necrosis factor Rattus norvegicus
8 Repeated administration of low doses of rTNF to TB rats induces mild reduction in tumor growth, tolerance to the cachectic effects of rTNF that results in tolerance to the cachectic effects of tumor, and prolongation of survival. Terbium tumor necrosis factor Rattus norvegicus
9 Repeated administration of low doses of rTNF to TB rats induces mild reduction in tumor growth, tolerance to the cachectic effects of rTNF that results in tolerance to the cachectic effects of tumor, and prolongation of survival. Terbium tumor necrosis factor Rattus norvegicus