Title : Biomarkers for non-human primate type-I hypersensitivity: antigen-specific immunoglobulin E assays.

Pub. Date : 2013 Jun 28

PMID : 23541488






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This assay confirmed that plasma from animals identified as positive in the drug-specific IgE immunoassay contained biologically active IgE (i.e. could sensitize cultured mast cells), resulting in histamine release after exposure to the therapeutic antibody. Histamine immunoglobulin heavy constant epsilon Homo sapiens
2 This assay confirmed that plasma from animals identified as positive in the drug-specific IgE immunoassay contained biologically active IgE (i.e. could sensitize cultured mast cells), resulting in histamine release after exposure to the therapeutic antibody. Histamine immunoglobulin heavy constant epsilon Homo sapiens