Title : Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production.

Pub. Date : 2013 Apr 9

PMID : 23530236






2 Functional Relationships(s)
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1 RNAi-mediated knockdown of INSL3 reduced INSL3 mRNA (75%) and protein (94%) level and elicited a 77% reduction in CYP17A1 mRNA and 83% reduction in androstenedione secretion. Androstenedione insulin like 3 Homo sapiens
2 Conversely, treatment with exogenous (human) INSL3 increased androstenedione secretion ~twofold. Androstenedione insulin like 3 Homo sapiens